GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs4905558 | 1 | rs4905560 | chr14:97354740 | VRK1 | chr14:97263684-97347950:+ | 0.17 | 3.96 | 8.49E-5 | Neutrophil count |
| THCA | cis | rs4906172 | 1 | rs4906172 | chr14:102454933 | RAGE | chr14:102690838-102771531:- | -0.15 | -4.72 | 3.05E-6 | Menopause (age at onset) |
| THCA | cis | rs4906172 | 1 | rs4906174 | chr14:102495144 | RAGE | chr14:102690838-102771531:- | -0.15 | -4.76 | 2.59E-6 | Menopause (age at onset) |
| THCA | cis | rs2273905 | 1 | rs4906205 | chr14:102932447 | ANKRD9 | chr14:102973198-102976128:- | 0.15 | 3.37 | 0.000821 | QT interval |
| THCA | cis | rs4907240 | 1 | rs4907240 | chr2:97228039 | ANKRD36B | chr2:98109130-98206428:- | 0.18 | 3.6 | 0.000353 | Event-related brain oscillations |
| THCA | cis | rs6041 | 1 | rs491098 | chr13:113769346 | F7 | chr13:113760105-113774994:+ | 0.26 | 3.79 | 0.000169 | End-stage coagulation |
| THCA | cis | rs6088813 | 1 | rs4911178 | chr20:33952620 | CEP250 | chr20:34042996-34099802:+ | -0.15 | -3.37 | 0.000804 | Height |
| THCA | cis | rs6088813 | 1 | rs4911178 | chr20:33952620 | CPNE1 | chr20:34213968-34262539:- | 0.3 | 5.95 | 5.17E-9 | Height |
| THCA | cis | rs6088813 | 1 | rs4911178 | chr20:33952620 | GDF5 | chr20:33897002-34042568:- | -0.18 | -3.81 | 0.000154 | Height |
| THCA | cis | rs6088813 | 1 | rs4911178 | chr20:33952620 | UQCC | chr20:33890383-33999833:- | 0.32 | 10.23 | 2.48E-22 | Height |
| THCA | cis | rs6088813 | 1 | rs4911180 | chr20:33972948 | CEP250 | chr20:34042996-34099802:+ | -0.15 | -3.4 | 0.00073 | Height |
| THCA | cis | rs6088813 | 1 | rs4911180 | chr20:33972948 | CPNE1 | chr20:34213968-34262539:- | 0.31 | 5.99 | 4.19E-9 | Height |
| THCA | cis | rs6088813 | 1 | rs4911180 | chr20:33972948 | GDF5 | chr20:33897002-34042568:- | -0.18 | -3.83 | 0.000146 | Height |
| THCA | cis | rs6088813 | 1 | rs4911180 | chr20:33972948 | UQCC | chr20:33890383-33999833:- | 0.32 | 10.13 | 5.71E-22 | Height |
| THCA | cis | rs4911414 | 1 | rs4911409 | chr20:32710710 | RALY | chr20:32581732-32672675:+ | 0.14 | 4.32 | 1.89E-5 | Tanning;Skin sensitivity to sun;Red vs. non-red hair color;Freckles;Burning and freckling |